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Geraghty, Z., Barnard, C., Uluocak, P. and U. Gruneberg. (2021) The association of Plk1 with the Astrin-Kinastrin complex promotes formation and maintenance of a metaphase plateJ Cell Sci. doi: 10.1242/jcs.251025


Bancroft, J., Holder, J., Geraghty, Z., Barr, F.A. and U. Gruneberg. (2020) PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20. Mol. Cell Biol. doi: 10.1091/mbc.E20-04-0252

Legal, T., Hayward, D., Gluszek-Kustusz, A., Blackburn, E.A., Spanos, C., Rappsilber, C., Gruneberg, U., and Welburn, J. (2020) The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment. J Cell Sci. doi: 10.1242/jcs.246025


Poser, E., Caous, R., Gruneberg, U., and Barr, F.A. (2019) Aurora A promotes chromosome congression by activating the condensin-dependent pool of KIF4A. J Cell Biol. 219, doi: 10.1083/jcb.201905194

Hayward, D., Alfonso-Perez, T. and Gruneberg, U. (2019) Orchestration of the spindle assembly checkpoint by CDK1-cyclin B1. FEBS Letters (Special Issue on Cell Cycle Control). 593, 2889-2907 

Hayward, D., Bancroft, J., Mangat, D., Alfonso-Perez, T., Dugdale, S., McCarthy, J., Barr, F.A. and Gruneberg, U. (2019) Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56. J Cell Biol. 218, 3188-3199

Hayward, D., Alfonso-Pérez, T., Cundell, M.J., Hopkins, M., Holder, J., Bancroft, J., Hutter, L. H., Novak, B., Barr, F. A. and Gruneberg U. (2019) CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization. J. Cell Biol. 218, 1108–1117 

Alfonso-Pérez, T., Hayward, D., Holder, J., Gruneberg, U. and Barr, F. A. (2019) MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling. J. Cell Biol. 218, 1182-1199


Gruneberg, U. and Barr, F. (2017) Organelle inheritance - what players have skin in the game? Science 355, 459-460.


Espert, A., Uluocak, P., Nunes Bastos, R., Mangat, D., Graab, P. and Gruneberg, U. (2014) PP2A-B56 promotes spindle assembly checkpoint silencing by dephosphorylating Knl1. J. Cell Biol. 206, 833-842.


Cundell, M.J., Bastos, R.N., Zhang, T., Holder, J., Gruneberg, U., Novak, B. and Barr, F.A. (2013) The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation. Mol. Cell 52, 393-405.

Nunes Bastos, R., Gandhi, S.R., Baron, R.D., Gruneberg, U., Nigg, E.A. and Barr, F.A. (2013) Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. J Cell Biol. 202, 605-621.

Hammond, D., Zeng, K., Espert, A., Bastos, R.N., Baron, R.D., Gruneberg, U*. and Barr, F.A*. (2013) Melanoma-associated mutations in protein phosphatase 6 cause chromosome instability and DNA damage owing to dysregulated Aurora A . J Cell Sci. 126, 3429-3440. *joint corresponding authors


Dunsch, A.K., Hammond, D., Lloyd, J., Schermelleh, L., Gruneberg, U, Barr F.A. (2012) Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation. J Cell Biol. 198, 1039-54.


Barr, F.A., Elliot, P. and Gruneberg, U. (2011) Protein phosphatases and the regulation of mitosis. J Cell Sci. 124, 2323-2334.

Dunsch, A.K., Linnane, E., Barr, F.A. and Gruneberg, U. (2011) The astrin-kinastrin/SKAP complex localizes to microtubule plus-ends and controls chromosome alignment. J Cell Biol. 192, 959-968. 


Zeng, K., Nunes-Bastos, R., Barr, F.A*. and Gruneberg, U*. (2010) Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A in complex with TPX2. J Cell Biol. 191, 1315-1332. *joint corresponding authors


Barr, F.A. and Gruneberg, U. (2007) Cytokinesis: Placing and making the final cut. Cell 131, 847-855.

Thein, K.H., Kleylein-Sohn, J., Nigg, E.A. and Gruneberg, U. (2007) Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol. 178, 345-354.  

Neef, R., Gruneberg, U., Kopajtich, R., Körner, R., Nigg, E.A. Sillje, H. and Barr, F.A. (2007) Choice of Plk1 docking partners during mitosis is controlled by the activation state of Cdk1. Nat Cell Biol. 9, 436-444. 


Klein, U.R., Nigg, E.A. and Gruneberg, U. (2006) Centromere targeting of the chromosomal passenger complex requires a ternary sub-complex of Borealin, Survivin and the very N-terminal domain of INCENP. Mol.Biol.Cell. 17, 2547-2558.

Gruneberg, U., Neef, R., Li, X., Chan, E.H.Y., Chalmalasetty, R.B., Nigg, E.A. and Barr, F.A. (2006) KIF14 and citron kinase act together to promote efficient cytokinesis. J Cell Biol. 172, 363-372. 


Neef, R., Gruneberg, U., Barr, F.A. (2005) Assay and functional properties of Rabkinesin-6/Rab6-KIFL/MKlp2 in cytokinesis. Methods Enzymol. 403, 618-628.


Mishima, M., Pavicic, V., Gruneberg, U., Nigg, E.A. and Glotzer, M. (2004) Cell cycle regulation of central spindle assembly. Nature 430, 908-913.

Gruneberg, U., Neef, R., Honda, R., Nigg, E.A. and Barr, F.A. (2004). Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol. 166, 167-172. 


Gruneberg, U. and Nigg, E.A. (2003) Regulation of cell division: stop the SIN! Trends Cell Biol. 13,159-162. 


Gruneberg, U., Glotzer, M., Gartner, A. and Nigg, E.A. (2002). The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. J Cell Biol. 158, 901-914. 


Gruneberg, U., Campbell, K., Simpson, C., Grindlay, J. and Schiebel, E. (2000). Nud1p links astral microtubule organisation and control of the exit from mitosis. EMBO J. 19, 6475-6488. 

van Ham, M., van Lith, M., Lillemeier, B., Tijn, E., Gruneberg, U., Rahman, D., Pastoors, L., van Meijgarden, K., Roucard, C., Trowsdale, J., Ottenhof, T., Pappin, D. and Neefjes, J. (2000). Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J. Exp. Med. 191, 1127-1135. 


Pereira, G., Gruneberg, U.*, Knop, M. and Schiebel, E. (1999). Interaction of the yeast gamma-tubulin complex-binding protein Spc72p with Kar1p is essential for microtubule function during karyogamy. EMBO J. 18, 4180-4195. (*joint first author) 

Hitzel, C., Gruneberg, U., van Ham, S. M., Trowsdale, J. and Koch, N. (1999). Sodiumdodecyl sulfate-resistant HLA-DR “superdimer” bands are in some cases class II heterodimers bound to antibody. J. Immunol. 162, 4671-4676. 


Rich, T., Gruneberg, U. and Trowsdale, J. (1998). Heat shock proteins, HLA-DR and rheumatoid arthritis. Nat Med. 4, 1210-1.


Gruneberg, U., Rich, T., Roucard, C., van Ham, S. M., Charron, D., and Trowsdale, J. (1997). Two widely-used anti-DRa antibodies bind to an intracellular C-terminal epitope. Human Immunology 53, 34-38.

Ullrich, H. J., Doring, K., Gruneberg, U., Jahnig, F., Trowsdale, J., and van Ham, S. M. (1997). Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH. Proc. Natl. Acad. Sci. USA 94, 13163-13168.

van Ham, S. M., Tijn, E. P. M., Lillemeier, B. F., Gruneberg, U., van Meijgaarden, K. E., Pastoors, L., Verwoerd, D., Tulp, A., Canas, B., Rahman, D., Ottenhoff, T. H. M., Pappin, D. J. C., Trowsdale, J., and Neefjes, J. (1997). HLA-DO is a negative regulator of HLA-DM-mediated MHC class II peptide loading. Current Biology 7, 950-957.


Beck, S., Belich, M., Gruneberg, U., Jackson, A., Kelly, A., Sanseau, P., Sanderson, F., Trowsdale, J., Van Ham, M. (1996).Organisation and functions of class II genes and molecules. DNA Seq. 7, 21-23.

van Ham, S. M., Gruneberg, U., Malcherek, G., Bröker, I., Melms, A., and Trowsdale, J. (1996). Human Histocompatibility Leukocyte Antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs. J. Exp. Med. 184, 2019-2024. 


Schild, H., Gruneberg, U., Pougialis, G., Wallny, H.-J., Keilholz, W., Stevanovic, S., and Rammensee, H.-G. (1995). Natural ligand motifs of H2-E molecules are allele-specific and illustrate homology to HLA-DR molecules. International Immunology 7, 1957-1965.